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. Author manuscript; available in PMC: 2022 Feb 15.
Published in final edited form as: Cell Rep. 2021 Oct 12;37(2):109813. doi: 10.1016/j.celrep.2021.109813

Figure 2. MAFA protein levels were transiently upregulated at 4 weeks in male MafAS64F/+ islets.

Figure 2.

(A) Immunostaining over the course of 3, 4, 5, 6, and 7 weeks revealed that MAFA protein staining intensity only increased at 4 weeks of age in male MafAS64F/+ (Het) islets.

(B) In contrast, MAFA staining intensity was unchanged between female MafAS64F/+ and WT islets.

(C) MafA mRNA levels were significantly reduced at 4 and 5 weeks in both male and female MafAS64F/+ islet samples. Fold change shown relative to male WT islets. Two-tailed Student t test; *p < 0.05; scale bars, 50 μm.