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. 2021 Oct 27;66(2):223–234. doi: 10.1165/rcmb.2021-0192OC

Figure 6.


Figure 6.

The Plk1-Casp9/3 pathway is upregulated in asthmatic HASM cells. (A) Representative IBs illustrating Plk1 expression, Casp9 phosphorylation, and pro-Casp9/3 concentrations in nonasthmatic and asthmatic HASM cells. (BF) Protein expression and phosphorylation in asthmatic (AS) cells are compared with nonasthmatic (N) cells. Casp9 phosphorylation is determined using pSer-196 or pThr-125/total pro-Casp9 ratios. Data are mean values of four asthmatic cell cultures from three donors. Error bars indicate SD. **P < 0.01. Student’s t-test was used for statistical analysis.