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Main Features of Experimental ALI
| Main Features | |
|---|---|
| Rapid onset (with a defined period of time, specific to the model utilized) plus*: | |
| Histological evidence of tissue injury | |
| Alteration of the alveolar–capillary barrier | |
| Presence of an inflammatory response | |
| Evidence of physiological dysfunction |
Definition of abbreviation: ALI = acute lung injury.
To state ALI has occurred, at least one accepted “relevant” measurement under at least three out of four domains should be reported.
