Table 1.
n = 13 | |
---|---|
Age, y | 79.6 ± 12.7 |
Sex, male:female | 12:1 |
Illness duration, d | 21.5 ± 10.4 |
Clinical and radiological features | |
Hypoxic respiratory failure | 13 (100) |
Thoracic radiology | |
Pulmonary GGO | 13 (100) |
Pulmonary embolism | 3 (23.1) |
Supportive care | |
Supplemental oxygen | 13 (100) |
Invasive mechanical ventilation | 4 (30.8) |
Duration (intubation to death), d | 18.3 ± 7.8 |
Vasopressors | 4 (30.8) |
Renal replacement therapy | 3 (23.1) |
Histological findings | |
Lung* | |
Inflammation | 13 (100) |
Diffuse alveolar damage | 9 (69.2) |
Thrombosis | 4 (30.8) |
Spleen | |
Reactive plasmacytosis | 13 (100) |
White pulp atrophy | 5 (38.5) |
SARS-CoV-2 RNA detected | |
Spleen | 5 (38.5) |
Lung* | 8 (61.5) |
Definition of abbreviations: GGO = ground glass opacification; SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2.
Data are presented as mean ± SD or absolute number (% of total).
Findings in right middle lobe (same lobe used for proteomic analysis).