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. 2021 Oct 28;66(2):196–205. doi: 10.1165/rcmb.2021-0358OC

Table 1.

Characteristics of Patients with Fatal COVID-19

  n = 13
Age, y 79.6 ± 12.7
Sex, male:female 12:1
Illness duration, d 21.5 ± 10.4
Clinical and radiological features  
 Hypoxic respiratory failure 13 (100)
 Thoracic radiology  
  Pulmonary GGO 13 (100)
  Pulmonary embolism 3 (23.1)
Supportive care  
 Supplemental oxygen 13 (100)
 Invasive mechanical ventilation 4 (30.8)
  Duration (intubation to death), d 18.3 ± 7.8
 Vasopressors 4 (30.8)
 Renal replacement therapy 3 (23.1)
Histological findings  
 Lung*  
  Inflammation 13 (100)
  Diffuse alveolar damage 9 (69.2)
  Thrombosis 4 (30.8)
 Spleen  
  Reactive plasmacytosis 13 (100)
  White pulp atrophy 5 (38.5)
SARS-CoV-2 RNA detected  
 Spleen 5 (38.5)
 Lung* 8 (61.5)

Definition of abbreviations: GGO = ground glass opacification; SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2.

Data are presented as mean ± SD or absolute number (% of total).

*

Findings in right middle lobe (same lobe used for proteomic analysis).