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. 2022 Feb 7;2022:8217663. doi: 10.1155/2022/8217663

Figure 1.

Figure 1

The associations between MPO/HOCl and hSOD1G93A ALS. (a) The levels of plasma HOCl in healthy control and ALS patients. P < 0.01, Student's t-test. (b) The correction of plasma HOCl levels and ALSFRS-R scores in ALS patients (Spearman's rho = 0.6663, P < 0.01). (c) The time course analysis of endogenous HOCl and transfection efficiency in transiently transfected hSOD1G93A NSC-34 cells. Bar = 200 μm. (d, e) The quantitative analysis of fluorescent intensity of HKOCl-3 in cell and supernatant. &P < 0.05 vs. 72 h in hSOD1G93A NSC-34 cells, one-way ANOVA followed by LSD tests. @P < 0.05 vs. vector, Student's t-test. ∗P < 0.05 vs. hSOD1WT. (f) The cell death of transiently transfected hSOD1G93A NSC-34 cells, as measured by western blot.