Table 2.
Treatment option | Proctitis | Left-sided and extensive | ||
Standard | Optimised | Standard | Optimised | |
A | Rectal 5-ASA | Rectal 5-ASA (following rectal 5-ASA induction) | Low-dose oral 5-ASA | Low-dose oral 5-ASA with FC (following low-dose combined 5-ASA induction) |
B | Low-dose oral 5-ASA with FC (following topical steroids or low-dose combined 5-ASA induction) | High-dose oral 5-ASA (following high-dose combined 5-ASA induction) | ||
C | Combined 5-ASA (following high-dose combined 5-ASA induction) | Combined 5-ASA (following budesonide MMX induction) |
5-ASA, 5-aminosalicylate; mesalazine; FC, faecal calprotectin; MMX, Multi Matrix.