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. 2022 Feb 10;10(1):e002275. doi: 10.1136/bmjdrc-2021-002275

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Type 2 diabetes and lnFG path analysis models. In the pooled analysis, rs373863828 genotype (Gt) has both direct (blue) and indirect (red) effects on (A) T2D and (B) lnFG as mediated by lnBMI. All direct paths shown have p<0.001. lnBMI, log-transformed body mass index; lnFG, log-transformed fasting glucose; T2D, type 2 diabetes.