Table 3.

A linear model was built for each predictor relative to the outcome 12 months postoperative change on the iNPH scale (delta iNPH scale) at follow-up and the covariates age, sex, waiting time for shunt surgery, iNPH scale score at baseline and Evans’ index

	Coefficient	Analysis of variance P-value
NfL (n = 187)	− 3.10	0.016
T-tau (n = 364)	− 2.45	0.012
P-tau (n = 362)	− 0.62	0.65
Aβ1–42 (n = 363)	2.76	0.058
DESH (n = 376)	4.30	0.055
Covariates:
Age	− 0.50	< 0.001
Sex	− 1.39	0.42
Time to shunt	− 6.03	< 0.001
iNPH scale baseline	− 0.23	< 0.001
Evans´ index	20.08	0.33

iNPH idiopathic normal pressure hydrocephalus, NfL neurofilament light protein, T-tau total tau, P-tau phosphorylated tau, Aβ1–42 amyloid beta-42; DESH disproportionately enlarged subarachnoid-space hydrocephalus

Bold numbers are significant