Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 14;22:81. doi: 10.1186/s12935-022-02497-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 1 — Expression pattern of circ_IRAK3 in BC tissues and cells. A The expression of circ_IRAK3 in BC tissues (compared to adjacent non-cancerous tissues) was estimated by qRT-PCR. B Kaplan–Meier curves of overall survival for BC patients with high or low expression of circ_IRAK3. The cutoff value was the median of circ_IRAK3 expression in 47 BC patients, of which 23 were classified as low expression and 24 were classified as high expression. C Relative expression of circ_IRAK3 in BC cells (HCC70 and MDA-MB-231) (compared with MCF-10A cells) was evaluated by qRT-PCR. D, E The levels of circ_IRAK3 and IRAK3 mRNA in total RNA of HCC70 and MDA-MB-231 under RNase R treatment were analyzed by qRT-PCR. F, G Following the nuclear-cytoplasmic fractionation assay, the abundance of circ_IRAK3 in the nuclear and cytoplasmic portions was analyzed by qRT-PCR. *P < 0.05