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[Preprint]. 2022 Feb 9:2022.02.08.22270676. [Version 1] doi: 10.1101/2022.02.08.22270676

Table 2.

Incremental dose administered per route/regimen for the first 18 subjects as a sentinel group for safety monitoring (IM=intramuscular; IN=intranasal; S=subject)

1st Dose Low Dose (LD)
(107.0 EID50%/dose)
Medium Dose (MD)
(107.5 EID 50%/dose)
High Dose (HD)
(108.0 EID 50%/dose)
Day1 Day 2 Day3 Day 4 Day 5 Day 6 Day 7 Day 8 Day 9
IM S1 S3 S5 S7 S9 S11 S13 S15 S17
IN S2 S4 S6 S8 S10 S12 S14 S16 S18
Evaluation by an Independent Safety Committee 7 days after last High Titer vaccination