Table 1. Effect of HIV infection on CD4+/CD25hi/CD127low T lymphocyte counts.
| Variable | ART-naive PLWHA (n=70) | Healthy controls (n=30) | Test | P |
|---|---|---|---|---|
| Age in years, mean (SD) | 31.7±(5.6) | 30.2±(9.8) | 0.869 | 0.388 |
| CD4+/CD25hi/CD127low T | 10.3±6.0 | 31.7±8.0 | 54.415 | 0.000 |
| CD4+/CD25hi/CD127low T/CD3(%) | 0.9±0.5 | 2.4±0.8 | 35.727 | 0.000 |
| CD3+ T lymphocyte counts (cells/uL) | 1,017.2±376.2 | 1,377.4±310.5 | 10.928 | 0.001 |
| CD4+ T lymphocyte counts (cells/uL) | 205.7±111.9 | 685.9±172.6 | 64.695 | 0.000 |
| CD8+ T lymphocyte counts (cells/uL) | 722.8±315.9 | 551.1±186.4 | 5.537 | 0.015 |
| CD4/CD8 | 0.3±0.2 | 1.3±0.4 | 68.742 | 0.000 |
| HBV coinfection | 7 (10.0) | 2 (6.7) | 0.285 | 0.594 |
| HCV coinfection | 0 (0) | 0 (0) | --- | --- |
| Syphilis coinfection | 15 (21.4) | 0 (0) | 7.563 | 0.006* |
PLWHA = People living with HIV/AIDS.