Figure 6.

Ratio of ESTIMATE stroma and immune scores in rectal cancers. A, Receiver operating characteristic (ROC) curve assessing ratio of ESTIMATE stromal to immune scores (S:I) as predictor of recurrence. Using the Youden criterion, the optimal cut‐off is S:I = 1.24, with area under the curve (AUC) = 0.64. B, Disease‐free survival by S:I, with low S:I defined as ≥1.24, the cut‐off value on the ROC curve. [Colour figure can be viewed at wileyonlinelibrary.com]