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. 2022 Feb 1;8:810494. doi: 10.3389/fnut.2021.810494

Table 2.

Subgroup analysis of metabolic syndrome (MetS) for the highest vs. lowest dietary iron level category.

Stratification Number of studies Pooled RR 95% CI P- value Heterogeneity
All studies 7 1.27 1.12, 1.44 P < 0.001 P = 0.01; I2 = 44%
Study design
Cross-sectional 5 1.31 1.13, 1.52 P < 0.001 P = 0.12; I2 = 45%
Cohort 2 1.34 0.72, 2.47 P = 0.35 P = 0.10; I2 = 62%
Race
Asian 4 1.44 1.13, 1.83 P = 0.003 P = 0.10; I2 = 53%
American 3 1.04 0.81, 1.32 P = 0.77 P = 0.69; I2 = 0%
Diagnostic criteria of MetS
NCEP ATP III 4 1.59 1.30, 1.93 P < 0.001 P = 0.75; I2 = 0%
Other 3 1.08 0.91, 1.27 P = 0.37 P = 0.62; I2 = 0%
Sample size
<1,000 2 0.94 0.53, 1.66 P = 0.83 P = 0.43; I2 = 0%
>1,000 5 1.34 1.09, 1.65 P = 0.006 P = 0.06; I2 = 56%
Exposure assessment
FFQ 1 2.04 0.97, 4.29 / /
24 h or 3 days recall 6 1.25 1.10, 1.42 P < 0.001 P = 0.10; I2 = 45%
Type of iron
Heme iron 5 0.98 0.79, 1.22 P = 0.88 P = 0.04; I2 = 61%
Non-heme iron 5 1.25 1.08, 1.46 P = 0.004 P = 0.18; I2 = 36%