Babul 2003.
| Methods | Randomised (random‐numbers table), concealed allocation and patient and assessor blind. No report of intention‐to‐treat analysis or of exclusions. | |
| Participants | 16 healthy female volunteers. Underwent deliberately provocative exercise of non‐dominant quadriceps muscle. | |
| Interventions | HBOT
100% oxygen at 2.0 ATA for 60 minutes at 4, 24, 48 and 72 hours post‐injury. CONTROL Sham HBOT at 1.2 ATA on air on the same schedule. |
|
| Outcomes | PAIN SCORE
Visual analogue scale (0 to 10) STRENGTH Change from baseline expressed as maximum eccentric torque in Nm. SWELLING Tape measurement by blinded researcher at a standard point. expressed relative to pre‐injury value. |
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| Notes | Schulz rating:
Randomisation ‐ A
Allocation concealment ‐ A
Completeness of outcome data ‐ A
Double‐blinding ‐ A
Very small study with multiple outcomes. Complex experimental design with 2 distinct phases with somewhat different therapy arms. |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Low risk | A ‐ Adequate |