Skip to main content
. 2005 Oct 19;2005(4):CD004713. doi: 10.1002/14651858.CD004713.pub2

Babul 2003.

Methods Randomised (random‐numbers table), concealed allocation and patient and assessor blind. No report of intention‐to‐treat analysis or of exclusions.
Participants 16 healthy female volunteers. Underwent deliberately provocative exercise of non‐dominant quadriceps muscle.
Interventions HBOT 
 100% oxygen at 2.0 ATA for 60 minutes at 4, 24, 48 and 72 hours post‐injury.
CONTROL 
 Sham HBOT at 1.2 ATA on air on the same schedule.
Outcomes PAIN SCORE 
 Visual analogue scale (0 to 10)
STRENGTH 
 Change from baseline expressed as maximum eccentric torque in Nm.
SWELLING 
 Tape measurement by blinded researcher at a standard point. expressed relative to pre‐injury value.
Notes Schulz rating: 
 Randomisation ‐ A 
 Allocation concealment ‐ A 
 Completeness of outcome data ‐ A 
 Double‐blinding ‐ A 
 Very small study with multiple outcomes.
Complex experimental design with 2 distinct phases with somewhat different therapy arms.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate