Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 11;6:e2100144. doi: 10.1200/CCI.21.00144

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by American Society of Clinical Oncology

PMC Copyright notice

FIG 2. — Technical architecture overview. The left side of the figure shows the full stack from the UIs at the top to the database at the bottom. The right side describes the stack in more detail. The top shows several ways that end users can access the annotations including the Genome Nexus Website, cBioPortal, potential other genomics websites, and the command-line interface. The middle shows what programmatic clients the end UIs leverage to request annotations from the REST API, and the bottom details the annotation retrieval from the database and external annotation sources. API, application programming interface; MAF, Mutation Annotation Format; REST, Representational State Transfer; UI, user interface; VCF, Variant Call Format.