TABLE 2.
Whole-genome sequencing results of azithromycin-resistant Shiga toxin-producing E. coli strains isolated between 2004 and 2020 in France
| Isolate | Collection yr | Patient age (yr) | Clinical diseasea | Quality sequencing data |
Serotype | Sequence type | Virulence factor(s) | Macrolide resistance gene(s) | ||
|---|---|---|---|---|---|---|---|---|---|---|
| N50 (bp) | Contig no. | Mean genome size (bp) | ||||||||
| 34396 | 2012 | 62 | HUS | 278,669 | 279 | 5,300,106 | O17/O44:H18 | 69 | Stx2d | mph(A), erm(B) |
| 36493 | 2013 | <1 | HUS | 94,290 | 408 | 5,562,733 | O26:H11 | 29 | Stx2d, Eaeβ1 | mph(A) |
| 42514 | 2017 | 28 | BD | 29,905 | 469 | 5,171,176 | O117:H7 | 6880 | Stx1a | mph(A) |
| 43037 | 2017 | 5 | HUS | 48,855 | 301 | 5,125,621 | O146:H8 | 8356 | Stx1c | mph(A) |
| 45195 | 2018 | 24 | BD | 39,047 | 332 | 5,095,835 | ND:H7 | 5292 | Stx1a | mph(A), erm(B) |
| 45381 | 2019 | 29 | BD | 52,202 | 318 | 5,272,679 | O146:H8 | 8356 | Stx1c | mph(A), mph(B) |
| 45466 | 2019 | 1 | BD | 64,220 | 472 | 5,942,917 | O26:H11 | 21 | Stx1a, Eaeβ1, EhxA | mph(G), mef(C) |
| 47439 | 2020 | 1 | HUS | 79,390 | 382 | 5,411,518 | O111:H8 | 16 | Stx1a, Stx2a, Eaeγ2, EhxA | mph(A) |
| 47750 | 2020 | 44 | BD | 70,538 | 333 | 5,642,051 | O157:H7 | 11 | Stx1a, Stx2c, Eaeγ1, EhxA | mph(B), erm(B) |
a
HUS, hemolytic uremic syndrome; BD, bloody diarrhea.