Table 1.
Top gene ontology terms associated with G207-induced gene expression changes.
| Term | FDRa | Countb | %c |
|---|---|---|---|
| Immune response | 4.80E-09 | 28 | 12.0 |
| Neutrophil chemotaxis | 3.80E-07 | 12 | 5.1 |
| Chemokine-mediated signaling pathway | 5.80E-07 | 12 | 5.1 |
| Monocyte chemotaxis | 1.50E-05 | 9 | 3.8 |
| Inflammatory response | 9.00E-05 | 20 | 8.5 |
| Antigen processing and presentation | 9.20E-05 | 9 | 3.8 |
| Lymphocyte chemotaxis | 2.20E-04 | 7 | 3.0 |
| Cell chemotaxis | 2.60E-04 | 9 | 3.8 |
| Chemical synaptic transmission | 3.30E-04 | 15 | 6.4 |
| Positive regulation of inflammatory response | 5.00E-04 | 9 | 3.8 |
| Cellular response to IFNγ | 8.70E-04 | 8 | 3.4 |
Note: The top 500 most variable genes identified through RNA-seq analysis were uploaded to the DAVID. The most significant biological processes associated with the 500 identified genes are displayed in the table.
aFDR, Benjamini FDR.
bCount, number of genes in our uploaded dataset of 500 that match with number of genes for that biological process.
cPercentage of genes in our uploaded dataset that match with number of genes for that biological process.