Table 2.
IDa | Term | FDRb | Countc | %d |
---|---|---|---|---|
GO:00006955 | Immune response | 2.08E-14 | 35 | 14.7 |
GO:0042110 | T-cell activation | 6.84E-07 | 11 | 4.6 |
GO:0032496 | Response to lipopolysaccharide | 8.04E-07 | 17 | 7.1 |
GO:0002250 | Adaptive immune response | 1.26E-04 | 14 | 5.9 |
GO:0006954 | Inflammatory response | 2.28E-04 | 21 | 8.8 |
GO:0050776 | Regulation of immune response | 6.79E-03 | 13 | 5.5 |
GO:0031295 | T-cell costimulation | 1.36E-02 | 9 | 3.8 |
GO:0045060 | Negative thymic T-cell selection | 1.46E-02 | 5 | 2.1 |
GO:0050852 | T-cell receptor signaling pathway | 4.25E-02 | 11 | 4.6 |
GO:0032715 | Negative regulation of IL6 production | 4.71E-02 | 6 | 2.5 |
GO:0032088 | Negative regulation of NF-κB transcription factor activity | 6.53E-02 | 8 | 3.4 |
GO:0030816 | Positive regulation of cAMP metabolic process | 7.15E-02 | 4 | 1.7 |
GO:0007166 | Cell surface receptor signaling pathway | 1.14E-01 | 14 | 5.9 |
GO:0042130 | Negative regulation of T-cell proliferation | 1.89E-01 | 6 | 2.5 |
GO:0010818 | T-cell chemotaxis | 1.96E-01 | 4 | 1.7 |
GO:0032720 | Negative regulation of tumor necrosis factor production | 2.16E-01 | 6 | 2.5 |
GO:0019835 | Cytolysis | 2.39E-01 | 5 | 2.1 |
GO:0006935 | Chemotaxis | 3.39E-01 | 9 | 3.8 |
GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | 4.43E-01 | 8 | 3.4 |
GO:0070098 | Chemokine-mediated signaling pathway | 5.51E-01 | 7 | 2.9 |
Note: Genes with significant P values in our Spearman rank-order analysis were uploaded into the DAVID database. The top 20 results sorted by decreasing FDR P value are displayed.
aID, GO database identifier.
bFDR, Benjamini FDR.
cCount, number of genes in our uploaded dataset of 500 that match with number of genes for that biological process.
dPercentage of genes in our uploaded dataset that match with number of genes for that biological process.