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. 2022 Feb 1;28(3):498–506. doi: 10.1158/1078-0432.CCR-21-2636

Table 2.

Biological processes which correlate with survival in post-G207 samples are associated with immune response.

IDa Term FDRb Countc %d
GO:00006955 Immune response 2.08E-14 35 14.7
GO:0042110 T-cell activation 6.84E-07 11 4.6
GO:0032496 Response to lipopolysaccharide 8.04E-07 17 7.1
GO:0002250 Adaptive immune response 1.26E-04 14 5.9
GO:0006954 Inflammatory response 2.28E-04 21 8.8
GO:0050776 Regulation of immune response 6.79E-03 13 5.5
GO:0031295 T-cell costimulation 1.36E-02 9 3.8
GO:0045060 Negative thymic T-cell selection 1.46E-02 5 2.1
GO:0050852 T-cell receptor signaling pathway 4.25E-02 11 4.6
GO:0032715 Negative regulation of IL6 production 4.71E-02 6 2.5
GO:0032088 Negative regulation of NF-κB transcription factor activity 6.53E-02 8 3.4
GO:0030816 Positive regulation of cAMP metabolic process 7.15E-02 4 1.7
GO:0007166 Cell surface receptor signaling pathway 1.14E-01 14 5.9
GO:0042130 Negative regulation of T-cell proliferation 1.89E-01 6 2.5
GO:0010818 T-cell chemotaxis 1.96E-01 4 1.7
GO:0032720 Negative regulation of tumor necrosis factor production 2.16E-01 6 2.5
GO:0019835 Cytolysis 2.39E-01 5 2.1
GO:0006935 Chemotaxis 3.39E-01 9 3.8
GO:0007169 Transmembrane receptor protein tyrosine kinase signaling pathway 4.43E-01 8 3.4
GO:0070098 Chemokine-mediated signaling pathway 5.51E-01 7 2.9

Note: Genes with significant P values in our Spearman rank-order analysis were uploaded into the DAVID database. The top 20 results sorted by decreasing FDR P value are displayed.

aID, GO database identifier.

bFDR, Benjamini FDR.

cCount, number of genes in our uploaded dataset of 500 that match with number of genes for that biological process.

dPercentage of genes in our uploaded dataset that match with number of genes for that biological process.