Table 1.
Baseline Characteristics of participants stratified by quartile of left atrial end diastolic volume index
| Quartile 1 (1.85-9.93 ml/m2) (n = 243) |
Quartile 2 (9.95- 13.36 ml/m2) (n = 248) |
Quartile 3 (13.37 – 18.54 ml/m2) (n = 242) |
Quartile 4 (18.60 – 89.03 ml/m2) (n = 205) |
p-value | |
|---|---|---|---|---|---|
| Demographics | |||||
| Age, years | 64.9±11 | 64.9±11 | 67.0±10 | 69.7±11 | <0.0001 |
| Male, % | 84.6 | 77.9 | 82.1 | 81.0 | 0.293 |
| Caucasian, % | 54.5 | 61.4 | 61.0 | 62.1 | 0.276 |
| Medical History | |||||
| MI, % | 56.7 | 49.4 | 57.0 | 54.1 | 0.297 |
| CHF, % | 13.1 | 13.0 | 17.6 | 28.7 | <0.0001 |
| Hypertension, % | 69.1 | 68.5 | 69.8 | 76.1 | 0.217 |
| Diabetes Mellitus, % | 26.4 | 27.0 | 26.5 | 24.7 | 0.941 |
| Stroke, % | 13.5 | 10.9 | 14.3 | 18.5 | 0.108 |
| Revascularization*, % | 59.8 | 48.8 | 60.4 | 66.4 | 0.001 |
| Angina, % | 39.8 | 35.4 | 34.2 | 40.1 | 0.439 |
| Current tobacco use, % | 24.8 | 21.4 | 18.4 | 14.9 | 0.144 |
| Medications | |||||
| Aspirin, % | 75.4 | 71.4 | 75.8 | 69.6 | 0.327 |
| Beta-blocker, % | 49.2 | 54.4 | 66.4 | 64.0 | <0.0001 |
| ACE-I or ARB, % | 22.3 | 22.1 | 25.8 | 29.8 | 0.002 |
| Diuretic, % | 26.2 | 20.7 | 32.0 | 34.2 | <0.0001 |
| Antiarrhythmic Drug, % | 2.5 | 3.6 | 6.6 | 13.0 | <0.0001 |
| Statin, % | 63.9 | 64.3 | 68.4 | 63.2 | 0.613 |
| Alcohol use, drinks/week | 2.3±3 | 2.4±3 | 2.4±3 | 2.1±2 | 0.390 |
| Physical Exam | |||||
| BMI, kg/m2 | 28.1±5 | 29.1±5 | 28.3±5 | 28.3±6 | 0.169 |
| BSA, m2 | 1.95±0.2 | 1.97±0.2 | 1.95±0.2 | 1.94±0.2 | 0.326 |
| SBP, mm Hg | 130.0±17 | 134.2±22 | 133.6±22 | 135.3±22 | 0.015 |
| DBP, mm Hg | 74.5±11 | 75.6±11 | 74.5±11 | 74.6±12 | 0.633 |
| Heart rate, beats/min | 71.2±12 | 68.5±11 | 66.2±11 | 66.1±12 | <0.0001 |
| Laboratory | |||||
| Troponin, ng/ml | 0.0012±.01 | 0.0004±.03 | 0.0044±.05 | 0.0064±.03 | 0.086 |
| NT-proBNP, pg/ml | 174± 425 | 216± 327 | 428± 664 | 1275± 3202 | <0.0001 |
| HDL, mg/dl | 46±13 | 46±14 | 45±14 | 46±14 | 0.833 |
| LDL, mg/dl | 108±31 | 105±36 | 105±35 | 99±30 | 0.022 |
| eGFR†, mg/dl | 63±4 | 64±3 | 63±4 | 62±6 | <0.0001 |
*
Surgical or percutaneous
†
Estimated glomerular filtration rate (eGFR) by Modification of Diet in Renal Disease equation
MI = myocardial infarction; CHF = congestive heart failure; ACE-I = angiotensin converting enzyme inhibitors; ARB = angiotensin receptor blockers; BMI = body mass index; BSA = body surface area; SBP = systolic blood pressure; DBP = diastolic blood pressure; NT-proBNP = N-terminal pro–B-type natriuretic peptide; HDL = high density lipoprotein; LDL = low density lipoprotein; eGFR = estimated glomerular filtration rate