FIG 1.

Additional value for empirical combination treatment with specific Gram-positive coverage and amikacin in patients with septic shock regarding antimicrobial susceptibility of the isolated microorganism. For specific Gram-positive coverage, (i) isolated microorganism was resistant to Gram-positive coverage in 69% of cases; (ii) isolated microorganism was susceptible to Gram-positive coverage, but another active antibiotic was also administered in 13% of cases; and (iii) Gram-positive coverage was the only active antibiotic in 18% of cases. For amikacin, (i) isolated microorganism was resistant to amikacin in 15% of cases; (ii) isolated microorganism was susceptible to amikacin, but another active antibiotic was also administered in 78% of cases; and (iii) amikacin was the only active antibiotic in 7% of cases. *, including glycopeptides (vancomycin and teicoplanin), daptomycin, and linezolid.