TABLE 2.

Etiological microorganisms in BSI episodes presenting with and without septic shock^a

Microorganism	All episodes (n = 1,563)	No septic shock (n = 1,306)	Septic shock (n = 257)	P value
Gram-positive cocci	656 (42)	600 (46)	56 (22)	<0.001
Coagulase-negative staphylococci	291 (19)	280 (21)	11 (4)	<0.001
S. aureus	72 (5)	65 (5)	7 (3)	0.142
MRSA	12 (17)*	8 (12)*	4 (57)*	0.120
Enterococcus spp.	222 (14)	205 (16)	17 (7)	<0.001
E. faecalis	66 (30)*	56 (27)*	10 (59)*	0.772
E. faecium	148 (67)*	142 (69)*	6 (35)*	<0.001
E. faecium, vancomycin resistant	10 (5)*	10 (5)*	0	0.383
Streptococcus spp.	98 (6)	76 (6)	22 (9)	0.098
S. pneumoniae	17 (17)*	10 (13)*	7 (32)*	0.006
Gram-negative bacilli	881 (56)	674 (52)	207 (81)	<0.001
E. coli	376 (24)	284 (22)	92 (36)	<0.001
ESBL	80 (21)*	67 (24)*	13 (14)*	0.962
Carbapenemase	2 (1)*	2 (1)*	0	1.000
Klebsiella spp.	137 (9)	103 (8)	34 (13)	0.006
ESBL	32 (23)*	27 (26)*	5 (15)*	0.900
Carbapenemase	3 (2)*	3 (3)*	0	1.000
P. aeruginosa	234 (15)	162 (12)	72 (28)	<0.001
MDR	59 (25)*	46 (28)*	13 (18)*	0.238
XDR	38 (16)*	30 (19)*	8 (11)*	0.438
Enterobacter spp.	56 (4)	49 (4)	7 (3)	0.418
AmpC-hyperproducer strain	9 (16)*	8 (16)*	1 (14)*	1.000
S. maltophilia	35 (2)	33 (3)	2 (1)	0.104
MDR-GNB	210 (13)	171 (13)	39 (15)	0.371
Candidemia	50 (3)	37 (3)	13 (5)	0.064
C. albicans	11 (22)*	6 (16)*	5 (38)*	0.009
Non-albicans candidemia	39 (78)*	31 (84)*	8 (62)*	0.487
Polymicrobial	180 (12)	146 (11)	34 (13)	0.347

^aAbbreviations: MRSA, methicillin-resistant S. aureus; ESBL, extended-spectrum β-lactamase; MDR, multidrug resistant; XDR, extensively drug resistant; GNB, Gram-negative bacilli. *, asterisk indicates percentage among its species.