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. 2022 Feb 15;66(2):e01744-21. doi: 10.1128/AAC.01744-21

TABLE 3.

Mortality according to active empirical antibiotic coverage administered in Gram-negative bloodstream infection with septic shocka

Active antibiotic(s) Survival, n (%) Death, n (%)
Only 1 β-lactam was active (n = 64) 22 (34) 42 (66)
Only amikacin was active (n = 10) 1 (10) 9 (90)
Combined β-lactam and amikacin were both active (n = 101) 62 (61) 39 (39)
Combined β-lactam, quinolone, and amikacin were all active (n = 4) 2 (50) 2 (50)
Combined β-lactam and quinolone were both active (n = 6) 4 (67) 2 (33)
No active empirical antibiotic was administered (n = 22) 3 (14) 19 (86)
a

P value for all data is <0.001.