Table 4. Summary of transcription levels across seven key developmental stages of Schistosoma haematobium.
| Developmental stage | Number of transcribed genesa (%) | Number of transcribed isoforms (%) | Average (mean) number of transcribed isoforms per gene | Median TPMb | Median TPM of top 1% transcribed isoforms | Key protein/pathway functions for top 1% transcribed isoforms |
|---|---|---|---|---|---|---|
| Egg (from urine) | 8153 (86.4) | 11,106 (75.6) | 1.4 | 15.0 | 1790 | Translation; RNA transport; ribosomal proteins |
| Egg (from hamster) | 7446 (79.0) | 9584 (65.2) | 1.3 | 9.95 | 1592 | Ubiquitin; protein folding, sorting and degradation; RNA transport; ribosomal proteins |
| Sporocyst | 6506 (69.0) | 7990 (54.4) | 1.2 | 5.95 | 1894 | Cellular nucleic acid-binding protein; RNA transport; ribosomal proteins |
| Cercaria | 7202 (76.4) | 9280 (63.1) | 1.3 | 5.74 | 1607 | Calmodulin; cytochrome c |
| Schistosomule | 7696 (81.6) | 10,657 (72.5) | 1.4 | 26.3 | 1391 | Peptidyl-prolyl isomerase; 14-3-3 protein beta; RNA transport, ribosomal proteins |
| Adult male | 8182 (86.8) | 11,935 (81.2) | 1.5 | 9.81 | 1702 | Glutathione S-transferase; peptidases/proteases |
| Adult female | 8112 (86.0) | 11,714 (79.7) | 1.4 | 7.79 | 2435 | Peptidases/proteases |
a TPM > 0.5
b transcripts per million