Skip to main content
. 2022 Feb 3;11:e74419. doi: 10.7554/eLife.74419

Table 1. Disease-related Tuberculosis ImmunoPhenotype QTL (TipQTL).

Multiple QTL within the same interval and clear allele effects are designated with the same TipQTL number. p-Values are determined by Churchill-Doerge permutations (Churchill and Doerge, 1994). Column headings: QTL, quantitative trait loci; Chr, chromosome; LOD, logarithm of the odds; CEQ, chromosomal equivalents.

QTL Trait Chr LOD p value Interval start (Mb) Peak (Mb) Interval end (Mb)
Tip5 Spleen CEQ 2 9.14 2.38E-02 174.29 178.25 178.25
Tip5 Spleen CFU 2 7.04 2.19E-01 73.98 174.29 180.10
Tip6 IL-9 2 8.61 4.52E-02 33.43 41.4 41.48
Tip6 IL-9 2 7.85 1.26E-01 22.77 24.62 25.65
Tip7 IL-17 15 7.84 5.27E-02 67.98 74.14 82.11
Tip8 CXCL1 7 7.57 1.06E-01 30.43 45.22 46.72
Tip8 Lung CFU 7 7.47 1.17E-01 31.06 37.78 45.22
Tip9 IL-10 17 7.16 1.85E-01 80.98 82.47 83.55
Tip10 Lung CFU 15 7.13 1.86E-01 77.00 78.16 78.70