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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Eur J Med Chem. 2021 Apr 8;219:113435. doi: 10.1016/j.ejmech.2021.113435

Figure 2.

Figure 2.

A. Structure of eIF4E bound to i4EG-BiP. The asymmetric unit consists of two cap-bound eIF4E structures, of which one shows density for the small molecule. B. i4EG-BiP density is unambiguously located between helix α1 and α2. C. Surface representation of the co-crystal structure shows the cavity into which i4EG-BiP binds.