TABLE 3.
Activity of antimicrobial agents against Alcaligenes spp. isolated from CF patients
| Antimicrobial combination | Concn tested (μg/ml) (range)a | % Synergistic activity | % Additive activity |
|---|---|---|---|
| Ciprofloxacin-piperacillin | 0.5–4, 8–256 | 6 | 10 |
| Ciprofloxacin-imipenem | 0.5–4, 0.5–16 | 5 | 27 |
| Ciprofloxacin-meropenem | 0.5–4, 0.5–16 | 9 | 23 |
| Ciprofloxacin–trimethoprim-sulfamethoxazole | 0.5–16, 1–8 | 1 | 0 |
| Ceftazidime–trimethoprim-sulfamethoxazole | 1–32, 1–8 | 4 | 3 |
| Ceftazidime-chloramphenicol | 1–32, 4–32 | 2 | 14 |
| Chloramphenicol–trimethoprim-sulfamethoxazole | 4–32, 1–32 | 1 | 12 |
| Chloramphenicol-minocycline | 4–32, 1–32 | 5 | 35 |
a
The first and second ranges of values given are for the first and second parts of the antimicrobial combination, respectively.