Figure 10.

Effect of PXR on the expression levels of inflammatory factors in Hepa1-6 cells. (A) mRNA and (B) protein expression levels of NF-κB, IL-1β, TNF-α, IL-6, NLRP3 and STAT3 in the three treatment groups. Data are expressed as the mean ± SD (n=6 per group). ^***P<0.001 compared with control group; ^##P<0.01 and ^###P<0.001 compared with empty plasmid group. NF-κB, nuclear factor-κB; IL, interleukin; TNF-α, tumour necrosis factor-α; NLRP3, NOD-like receptor protein 3; STAT3, signal transducer and activator of transcription 3; PXR, pregnane X receptor.