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. 2022 Feb 8;2022:6069682. doi: 10.1155/2022/6069682

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Copyright © 2022 Yu Pang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of let-7b inhibitor on PI3K/AKT/mTOR signaling pathway. (a) Typical Western blot diagram of the expression of each molecule. (b) Statistical graphs of beclin-1 expression in each group. (c) Statistical graphs of LC3II/LC3I expression in each group. (d) Statistical graphs of cleavage caspase 3 expression in each group. (e) Statistical graphs of PI3K expression in each group. (f) Statistical graphs of p-AKT expression in each group. (g) Statistical graphs of p-MTOR expression in each group. n = 6, ^∗ ^∗p < 0.01, and ^∗ ^∗ ^∗p < 0.001 versus control group; ^###p < 0.001 versus Aβ1-40 group, and p < 0.01 versus Aβ1-40 + let-7b mimic group.