Table 3.

Association of glucose variability parameters with nerve conduction parameters after adjustments

Variable	Composite Z‐score of NCV		Composite Z‐score of latency		Composite Z‐score of amplitude
	β	P‐value	β	P‐value	β	P‐value
Model 1
HbA1c	−0.313	<0.001	0.229	<0.001	−0.180	<0.001
Model 2
SDgluc	−0.124	0.021	0.048	0.367	−0.082	0.146
HbA1c	−0.245	<0.001	0.202	<0.001	−0.135	0.018
Model 3
MAGE	−0.066	0.181	0.045	0.354	−0.030	0.555
HbA1c	−0.291	<0.001	0.213	<0.001	−0.170	0.001
Model 4
CVgluc	−0.040	0.384	0.049	0.284	0.012	0.806
HbA1c	−0.310	<0.001	0.225	<0.001	−0.181	<0.001
Model 5
Average glucose	−0.100	0.058	0.017	0.747	−0.099	0.074
HbA1c	−0.258	<0.001	0.220	<0.001	−0.126	0.026

Model 1: adjusted for age, sex, body mass index (BMI), diabetes duration and hemoglobin A1c (HbA1c); model 2: adjusted for age, sex, BMI, diabetes duration, HbA1c and glucose standard deviation (SD_gluc); Model 3: adjusted for age, sex, BMI, diabetes duration and HbA1c, mean amplitude of glycemic excursions (MAGE); model 4: adjusted for age, sex, BMI, diabetes duration, HbA1c and glucose coefficient of variation (CV_gluc); model 5: adjusted for age, sex, BMI, diabetes duration, HbA1c and average glucose.

NCV, nerve conduction velocity.