Table 2.
Summary of included articles providing longitudinal data on conversion from MCI to dementia
| Authors | Country | Sample | Main assessment at baseline | Main outcome variable/s at baseline | Follow-up in months, mean (SD) | Non-converted/converted | Non-converted vs converted on the baseline assessment | MCI-converted (unimpaired/impaired at baseline) | Type of dementia |
|---|---|---|---|---|---|---|---|---|---|
| Visuospatial Working Memory (n=2) | |||||||||
| Ruggiero et al. (2020) [37] | Naples (Italy) | 10 aMCI | EAT | Allocentric-Coordinate Spatial Memory | NR | 2/8 | NR | 1/7 | AD |
| Wood et al. (2016) [66] | Falmer (UK) | 15 MCI [NOS] | 4MT | Allocentric Spatial Memory | 24 | 6/9 | Non-Converted > Converted | NR | AD |
| Awareness of Memory Deficits (n= 4) | |||||||||
| Bastin et al. (2021) [67] | Liège (Belgium) | 44 MCI (39 aMCI, 5 aMCI-md) | MARS-MFS | SRD | 21.40 (11.80) | 21/23 | Non-Converted > Converted | NR | AD |
| Munro et al. (2018) [68] | Boston (USA) | 33 aMCI | Memory composite score vs MFQ-general frequency of forgetting subscale | Deviation of the objective from the subjective memory measure | 19.10 (8.40) | 23/10 | Non-Converted > Converted | NR | AD |
| Nobili et al. (2010) [69] | Genoa (Italy) | 42 aMCI | MAC-Q | Self-evaluation of memory decline | 14.80 (6.40) | 24/16 (2 drop-outs) | NR | 9/7 | 14 AD, 1 FTD, 1 VaD |
| Spalletta et al. (2014) [70] | Rome (Italy) | 36 aMCI | MIQ-memory subscale | SRD | 60 | 26/10 | Non-Converted > Converted | NR | AD |
> , Better Performance, 4MT Four Mountains Test, AD Alzheimer’s Disease, aMCI Amnestic Mild Cognitive Impairment-Single Domain, aMCI-md Amnestic Mild Cognitive Impairment-Multiple Domain, EAT Ego-Allo Task, FTD Frontotemporal Dementia, MAC-Q Memory Complaint Questionnaire, MARS-MFS Memory Awareness Rating Scale-Memory Functioning Scale, MCI Mild Cognitive Impairment, MFQ Memory Functioning Questionnaire, MIQ Memory Insight Questionnaire, NOS Not Otherwise Specified, SRD Subjective Rating Discrepancy, VaD Vascular Dementia