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. 2022 Feb 2;13:773264. doi: 10.3389/fimmu.2022.773264

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Copyright © 2022 Lin, Wang, Xiong, Zhou, Yang, Chen, Xu, Zhou, Mao, Lv, Wang and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of potential immune subtypes of GBM. (A) Cumulative distribution function curve and (B) delta area of immune-related genes in TCGA cohort. (C) Sample clustering heat map. (D) Kaplan-Meier curves showing OS of GBM immune subtypes in TCGA cohort. (E) Overlap of GBM immune subtypes with three pan-cancer immune subtypes (NC1 = 2, NC4 = 158, NC5 = 1). (F) Distribution of four gene expression subtypes across IS1-IS3 in TCGA cohort. (G) Kaplan-Meier curves showing OS of GBM immune subtypes in CGGA cohort. *p < 0.05, **p < 0.01.