Figure 4.
Peak changes in (A) mean arterial blood pressure (MAP, P<0.001; n=6) and (B) muscle sympathetic nerve activity (MSNA, P=0.03; n=6) during isometric handgrip exercise were attenuated in postmenopausal women (PMW) following 1-month of transdermal estradiol (+E2) compared to baseline (-E2). Changes in (C) MAP (P=0.04; n=6) were also lower during post-exercise ischemia in PMW following 1-month of transdermal estradiol (+E2) compared to baseline (-E2), whereas (D) MSNA (P=0.27; n=6) was maintained. * P<0.05 between groups. Data expressed as mean±SE.