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. Author manuscript; available in PMC: 2022 Feb 16.
Published in final edited form as: Clin Trials. 2021 Nov 29;19(1):86–96. doi: 10.1177/17407745211046672

Appendix 4:

Post-hoc analysis examining the extent to which clustering was accounted for in sample size and analysis according to number and sources of clustering

Accounted for all sources of clustering?
Sources of clustering Sample size calculation Analysis
No sources of clustering (N=3) NA NA
One source of clustering (N=12) 4 (33.3%) 9 (75.0%)
 Repeated measures only (N=8) 2 (25%) 8 (100%)
 Cluster randomization only (N=3) 2 (66.7%) 1 (33.3%)
 Group treatment only (N=1) 0 0
Two sources of clustering (N=38) 4 (10.5%) 9 (23.7%)
 Repeated measures and multivariate/dyadic outcome (N=4) 0 0
 Cluster randomization and repeated measures (N=25) 3 (12.0%) 8 (32.0%)
 Cluster randomization and multivariate/dyadic outcome (N=1) 0 0
 Group treatment and repeated measures (N=8) 1 (12.5%) 1 (12.5%)
Three sources of clustering (N=9) 0 0
 Cluster randomization and repeated measures and multivariate/dyadic outcome (N=9) 0 0

NA: Not applicable