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. 2022 Feb 15;13:869. doi: 10.1038/s41467-022-28464-9

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Phylum level microbiome composition across all EstMB cohort subjects. b Functional profile of the microbiome across EstMB cohort subjects (KEGG domains). c PCA biplots on species-level taxonomic profiles colored by the relative abundance of the most dominant genus in the sample. EstMB Estonian Microbiome Project, KEGG Kyoto Encyclopedia of Genes and Genomes, PCA Principal component analysis.