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. 2021 Nov 23;11(1):277–292. doi: 10.1007/s40121-021-00566-9

Table 1.

Model parameters

Parameters Symbol Average value Range References
Duration of maternal antibody protection 1/ω 2 months 1–3 months [21, 22]
Duration of infectious period of 1st, 2nd and subsequent infections 1/γ1,2,3 10, 7, 5 days [23, 24]
Duration of short-term immunity of recovered individuals 1/p 18.7 months (half-life: 7.4 months) Estimated [25, 26]
Reduction of infectiousness for 2nd and subsequent infections ρ1,2 75%, 51% [4, 24, 2730]
Reduction of susceptibility after 1st, 2nd, and subsequent infections σ1,2 76%, 60%, 40% [4, 24, 2730]
Proportion of infections leading to lower respiratory tract infection by age groups d1,2,3

d1, 0–6 months: 0.5, d1, 7–12 months: 0.4, d1, 13–18 months: 0.3, d1, 19–24 months: 0.2, d1, 2–4 years: 0.15, d1, 5–9 years: 0.15, d1, 10–59 years: 0.1, d1, 60–64 years: 0.15, d1, 65–74 years: 0.25, d1, 75+ years: 0.4

d2 = 0.5 × d1

d3 = 0.25 × d1

Adapted from [4, 26, 28, 31]
Seasonality parameters b,φ 0.141, − 2.831 Estimated
Per contact transmission probability β0 0.0054 Estimated
Healthcare system use h 0.396 Estimated