TABLE 1.

Search strategy.

Concept 1	AND
treatment*(MeSH] OR
therap*(MeSH] OR
medicine*(MeSH] OR
drug*(MeSH] OR
agent*(MeSH]
Concept 2	AND
New(tiab] OR
Novel(MeSH]
Concept 3
drug induced liver injury, chronic(MeSH] OR
drug induced liver injury(MeSH] OR
drug induced liver disease(MeSH] OR
liver dysfunction(MeSH] OR
abnormalities, drug induced(MeSH] OR
DILI(tiab] OR
hepatotoxicit*(tiab] OR
toxic hepatitis(tiab]
Medline (via PubMed) search query
#4 Search (#1 AND #2 AND #3)
#3 Search (drug induced liver injury, chronic(MeSH] OR drug induced liver injury(MeSH] OR drug induced liver disease(MeSH] OR liver abnormalities, drug induced (MeSH] OR DILI(tiab] OR “toxic hepatitis”(tiab])
#2 Search (new(tiab] OR novel(tiab])
#1 Search (treatment*(tiab] OR therap*(MeSH] OR medicine*(MeSH] OR drug*(tiab] OR agent*(tiab])