TABLE 3.

Risk of bias across included studies.

Study	Selection bias (random sequence generation and allocation concealment)	Performance and detection bias (blinding to participants, personnel and outcome assessment)	Attrition bias (incomplete outcome data)	Reporting bias (selective reporting)	Other bias (including sample size estimation and intention-to-treat analysis)
Bicyclol
Naiqiong et al. (2017)	L	U	L	L	U
Calmangafodipir
Morrison et al. (2019)	L	H	L	L	H
Cytisin amidophosphate
Zhumadilov et al. (2012)	U	U	L	L	U
Fomepizole
Kang et al. (2020)	L/U	U	L	L	H
Zell Kanter et al. (2013)	H	H	U	U	U
Shah and Beuhler (2020)	H	H	U	U	U
Rampon et al. (2020)	H	H	U	U	U
Livina
Gulati et al. (2010)	L	H	U	L	U
Magnesium Isoglycyrrhizinate
Wang et al. (2019)	U	U	L	L	H
Picroliv
Bhosale et al. (2013)	U	U	U	H	U
Plasma exchange
Jothimani et al. (2018)	H	H	U	H	U
Aydemir et al. (2005)	H	H	U	H	U
Bilgir et al. (2013)	H	H	U	H	U
Liu et al. (2013)	H	H	U	H	U
Göpel et al. (2016)	H	H	U	H	U
Philips et al. (2017)	H	H	U	H	U
Riveiro-Barciela et al. (2019)	H	H	U	H	U
Rong et al. (2020)	H	H	U	H	U
Sinha et al. (2020)	H	H	L	U	U
Radix Paeoniae Rubra
Jing et al. (2017)	H	H	U	U	U
S-adenosylmethionine
Vincenzi et al. (2011)	H	H	U	L	L
Vincenzi et al. (2012)	H	H	U	L	U
Santini et al. (2003)	H	H	U	L	U