Table 3.
ReHo alterations of all participants.
| Main brain region | Hem | BA | MNI peak coordinate | Voxel size | t-value | ||
|---|---|---|---|---|---|---|---|
| X | Y | Z | |||||
| HC < active CD | – | – | – | – | – | – | – |
| Frontal superior medial | R | 10 | 6 | 69 | 9 | 91 | −3.29 |
| Frontal middle | L | 46 | −45 | 48 | 15 | 98 | −3.29 |
| HC > Active CD | – | – | – | – | – | – | - |
| Postcentral | R | 3 | 39 | −21 | 45 | 54 | 4.99 |
| Supplementary motor area | R | 4 | 6 | −21 | 57 | 30 | 4.68 |
| Temporal middle | L | 21 | −57 | −6 | −15 | 26 | 4.02 |
| HC < inactive CD | – | – | – | – | – | – | - |
| Frontal middle | L | 46 | −39 | 51 | 9 | 121 | −3.29 |
| HC > inactive CD | – | – | – | – | – | – | - |
| Precentral | R | 6 | 42 | −12 | 45 | 36 | 4.35 |
| Postcentral | R | 3 | 21 | −30 | 57 | 33 | 4.46 |
| Putamen | R | 48 | 33 | −9 | 3 | 25 | 4.12 |
| Active CD < inactive CD | – | – | – | – | – | – | - |
| Occipital middle | L | 19 | −42 | −81 | 27 | 14 | −2.61 |
| Active CD > inactive CD | – | – | – | – | – | – | - |
| Heschl | R | 48 | 48 | −21 | 9 | 9 | 3.24 |
| Temporal pole superior | R | 38 | 60 | 12 | −6 | 6 | 3.17 |
| Temporal superior | L | 48 | −54 | −15 | 0 | 6 | 3.21 |
Brain regions exhibiting significant differences in ReHo values among HC group, active CD group and inactive CD group.
The results employed age, gender, FD Jenkinson as covariates. The statistical threshold was set at voxel p <0.001, cluster p <0.01, and two tailed (GRF correction).
HC, healthy controls; CD, Crohn's disease; Hem, hemisphere; BA, Brodmann area; L, left; R, right.