Table 4.

Number of clinical trials in chronic diseases of interest by intervention types in Indigenous populations of Australia, Canada, New Zealand, and the United States.

Chronic condition	Intervention	Australia	Canada	New Zealand	United States
Arthritis	Combination a			1
	Drug/biological			2
Total = 3				3
Cardiovascular disease	Behavioral	2		7	2
	Combination a	4		4	2
	Device			1
	Drug/biological	2		1	1
	Other b	2			1
	Procedure/screening	2			1
Total = 32		12		13	7
Dental/periodontal disease	Behavioral	2		2	1
	Combination a	1			1
	Other b	2	1
Total = 10		5	1	2	2
Diabetes	Behavioral	1	2	5	8
	Combination a	1		2
	Device		2
	Drug/biological	2		1	2
	Other b	1			1
	Procedure/screening	1	1	1
Total = 31		6	5	9	11
Hypertension	Behavioral			1	7
	Device				1
	Other b		1
Total = 10			1	1	8
Kidney disease	Behavioral		1		2
	Other b				2
	Procedure/screening	1
Total = 6		1	1		4
Mental illness	Behavioral	9	3	8	29
	Combination a	1			2
	Device	1		1
	Drug/biological	2
	Other b	3		1
	Procedure/screening	1		1
Total = 62		17	3	11	31
Respiratory disease	Behavioral			1	2
	Combination a	1		3	2
	Drug/biological	2		2
	Other b	1
	Procedure/screening	1		1
Total = 16		5		7	4

Bold italic values indicates the total number of clinical trial studies per chronic disease per country.

^aCombination: a mix of Behavioral, Lifestyle, Education, and Rehabilitation interventions.

^bOther: gardening, digital stories, lifestyle coaching, case management, Ma ka hana ka Ike, Hanapū Provider Toolbox.