Table 2.
Characteristics of patients with a positive SARS-CoV-2 cell culture.
| Variable | Patient #1 | Patient #2 |
|---|---|---|
| History at time of first positive SARS-CoV-2 RT-PCR | 60 year old male with chronic lymphocytic leukemia who presented with cough and diarrhea. | 75 year old male with marginal zone lymphoma who presented with 2 weeks of cough. |
| Other medical conditions | Fibromyalgia | Hyperlipidemia |
| Hyperlipidemia | Deep vein thrombosis | |
| Acute hemolytic anemia | ||
| Positive SARS-CoV-2 RT-PCR tests (days after first positive test Day 0) (study samples in bold) | Day 0 | Day 0 |
| Day 81 | Day 57 | |
| Day 23 | Day 22 | |
| Day 111 | Day 67 | |
| Day 45 | Day 29 | |
| Day 120 | Day 79 | |
| Day 66 | Day 36 | |
| Day 43 | ||
| Malignancy treatment (last dose prior to positive test) | Obinutuzumab and venetoclax (Day -19) | Bendamustine and rituximab (Day -11) |
| SARS-CoV-2 antigen test | Positive | Negative |
| Cause of death | COVID-19 | Alive as of 16 months after COVID-19 diagnosis |
| SARS-CoV-2 cell culture results from the repeat test (plaque forming units/mL) | 27 PFU/mL | 2 x 106 PFU/mL |
| Spike protein mutations from the repeat test | D614G | D614G, S98F, S813l |