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. 2022 Feb 2;13:770948. doi: 10.3389/fnagi.2021.770948

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Copyright © 2022 Li, Li, Dai, Yang, Liang, Wang, Liu, Chen and Tao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experimental design of this study. (A,B) The experimental procedure of test with EA treatment. (C) The experimental procedure shows a strategy for EA treatment and hM4Di DREADDs inhibited. EA, electro-acupuncture; ¹H-MRS, PRESS-¹H Magnetic resonance spectroscopy; OFT, open field test; NOR, novel object recognition; NLR, novel location recognition; ITT, initial touch training; MTT, must touch training; PIT, punish incorrect training; LD, location discrimination.