Figure 1.

A summary of the overall associations between measurands and physiological and diet-related variables coloured by FDR p-values. Additionally, the age, sex and sterilization differences are summarized in the figure. The sex×sterilization interaction, breed, diet and fasting time differences, however, are not summarized due to the high number of variable levels and thus, complexity of the differences. The colour scale indicates the significance of the association between the measurand and variable: light yellow p > 0.05, yellow p = 0.01–0.05, orange p = 0.001–0.01 and red p < 0.001. Grey colour indicates that the variable did not affect metabolite measurand level and was thus not included in the multi-variable generalized linear model of that particular measurand. M, male; F, female; ster, sterilization; I, intact; N, neutered; sex*ster, interaction between sex and sterilization. The full names of the measurands are reported in electronic supplementary material, table S1.