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. 2021 May 13;16(4):833–845. doi: 10.1002/1878-0261.12962

Fig. 4.

Fig. 4

Comparison of the mutational profiles and mutational signatures of small cell carcinomas of the uterine cervix with SCLCs, HPV‐positive head and neck carcinomas, and HPV‐positive cervical carcinomas. (A) Comparison of somatic nonsynonymous mutations in small cell carcinomas of the uterine cervix (this study) with those of SCLCs and HPV‐driven head and neck and HPV‐driven cervical cancers (adenocarcinoma/ squamous cell carcinomas), showing the top 15 recurrently mutated genes across all studies. (B) Mutational signatures in small cell carcinomas of the uterine cervix subjected to WES (n = 6; this study), SCLCs, and HPV‐driven head and neck and HPV‐driven cervical cancers (adenocarcinoma/ squamous cell carcinomas). HNSC, head and neck squamous cell cancer; CESC, cervical adenocarcinoma/ squamous cell carcinomas.