Skip to main content
. 2021 Dec 9;3(2):100406. doi: 10.1016/j.patter.2021.100406

Figure 1.

Figure 1

Diagram of DeepAb method for antibody structure prediction

Starting from heavy and light chain sequences, the network predicts a set of inter-residue geometries describing the FV structure. Predictions are used for guided structure realization with Rosetta. Two interpretable components of the network are highlighted: a pre-trained antibody sequence model and output attention mechanisms.