Table 1.
Sociodemographic and clinical characteristics by exacerbation history. a
| Group A (n = 7788) |
Group B (n = 5151) |
Group C (n = 250) |
Groups B + C (n = 5401) |
Group D (n = 9273) |
|
|---|---|---|---|---|---|
| Female, n (%) | 3947 (50.7) | 3023 (58.7) | 141 (56.4) | 3164 (58.6) | 6221(67.1) |
| Age, mean (SD), years | 66.0 (10.8) | 65.3 (10.6) | 70.9 (10.6) | 65.6 (10.7) | 65.5 (10.6) |
| Smoking status, n (%) | |||||
| Current | 3890 (49.9) | 2702 (52.5) | 127 (50.8) | 2829 (52.4) | 4737 (51.1) |
| Ex | 2620 (33.6) | 1771 (34.4) | 84 (33.6) | 1855 (34.3) | 3366 (36.3) |
| Never | 257 (3.3) | 134 (2.6) | 5 (2.0) | 139 (2.6) | 244 (2.6) |
| Missing | 1021 (13.1) | 544 (10.6) | 34 (13.6) | 578 (10.7) | 926 (10.0) |
| BMI, n
mean (SD), kg/m2 |
5639 27.3 (6.2) |
3734 27.5 (6.2) |
182 25.9 (7.0) |
3916 27.4 (6.2) |
6777 27.5 (6.2) |
| Primary-care visits | |||||
| Any, median number | 12 | 12 | 15 | 12 | 15 |
| (Q1, Q3) | (7, 17) | (8, 18) | (9, 20) | (8, 18) | (10, 21) |
| COPD-related, median number | 9 | 10 | 11 | 10 | 12 |
| (Q1, Q3) | (6, 13) | (6, 14) | (7, 15) | (6, 14) | (8, 17) |
| Oxygen therapy, b n (%) | |||||
| Yes | 22 (0.3) | 11 (0.2) | 1 (0.4) | 12 (0.2) | 62 (0.7) |
| MRC dyspnea score, n | 5051 | 3322 | 149 | 3471 | 6164 |
| Median | 2 | 2 | 3 | 2 | 3 |
| (Q1, Q3) | (2, 3) | (2, 3) | (2, 3) | (2, 3) | (2, 3) |
| Comorbidities, n (%) | |||||
| Cardiovascular disease c | 1917 (24.6) | 1294 (25.1) | 94 (37.6) | 1388 (25.7) | 2522 (27.2) |
| Cerebrovascular disease | 929 (11.9) | 660 (12.8) | 45 (18.0) | 705 (13.1) | 1194 (12.9) |
| Diabetes mellitus | 1218 (15.6) | 826 (16.0) | 54 (21.6) | 880 (16.3) | 1505 (16.2) |
| Depression | 1739 (22.3) | 1255 (24.4) | 49 (19.6) | 1304 (24.1) | 2697 (29.1) |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; MRC, Medical Research Council; Q, quartile; SD, standard deviation.
a
Exacerbation history group: A, no exacerbations; B, 1 moderate exacerbation only; C, 1 severe exacerbation only; D, ⩾2 moderate or severe exacerbations.
b
Based on information from the physician and pharmacy (prescribed oxygen cylinders); excludes data on concentrator from the nurse/home visit database.
c
Combined with heart failure.