Table 1.
Summary of Cobb500 broiler chicken body weight in the high dose E.tenella challenge study (Study 4).
| Group | Mean body weight (g), (SD) | Mean body weight gain (g) | |||
|---|---|---|---|---|---|
| Day 7 | Day 21 | Day 31 | Pre-challenge (D7-21) | Post-challenge (D21-31) | |
| Unvaccinated, challenged (+) | 212 (13.58) | 1139 (112.2) | 2036 (191.3) | 926.9 (103.9) | 916.3 (123.5) |
| Unvaccinated, unchallenged (-) | 216.1 (15.23) | 1149 (124.2) | 2172 (263.3) | 933 (114.7) | 1058 (150.6)a |
| Empty vector vaccinated(pYD1 only), challenged | 208.3 (18.38) | 1112 (107.2) | 2094 (300) | 903.8 (100.9) | 977.1 (193.4) |
| pYD1-All 3 antigens, challenged | 211.6 (15.05) | 1108 (116.1) | 2223 (216.2) | 896.8 (108.4) | 1105 (124.1)ab |
| Number chickens per group | 28-32 | 28-32 | 19-21 | 28-32 | 19-21 |
| F statistic, p value (ANOVA) | 1.261, 0.29 | 0.8866, 0.45 | 2.319, 0.08 | 0.7825, 0.51 | 6.317, 0.0007 |
a
-significant difference compared to unvaccinated, challenged group, b-significant difference compared to empty vector vaccinated (pYD1 only), challenged group.
Chickens were weighed at day 7 (pre-vaccination), day 21 (day of challenge) and day 31 (10 days post-challenge).
Bold indicates significant difference between groups.