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STAT3 Degraders with Various Linker Compositions
| ||
|---|---|---|
| Cmpds | Linker | DC50 (STAT3, μM) Molm-16, 4h |
|
| ||
| SD-36 |
|
0.06 |
| 17 |
|
0.65 |
| 18 |
|
0.24 |
| 19 |
|
0.05 |
| 20 |
|
0.18 |
| 21 |
|
0.25 |
| 22 |
|
0.18 |
| 23 |
|
2.47 |
| 24 |
|
0.38 |
| 25 |
|
0.16 |
| 26 |
|
0.09 |
