Table 1. PDS-C increased the colony formation of granulocytic, erythroid, and megakaryocytic progenitor cells in normal mice (, n=8).
PDS-C (mg/L) | CFU-GM number (increasing %) | CFU-E number (increasing %) | CFU-MK number (increasing %) |
---|---|---|---|
0 | 97.0±11.5 | 117.0±11.2 | 56.0±6.5 |
5 | 108.2±12.8 (11.5±2.2) | 132.0±12.9 (12.8±2.3) | 63.1±7.7 (13.1±2.1) |
10 | 125.7±14.8** (28.5±3.4) | 148.4±15.7** (26.5±3.2) | 70.0±8.7** (25.7±3.1) |
25 | 137.5±16.4** (41.6±4.3) | 168.0±16.7** (42.4±4.5) | 78.2±8.5** (39.3±4.4) |
50 | 138.5±16.3** (42.2±4.6) | 167.2±16.9** (41.2±4.4) | 79.3±8.6** (40.9±4.3) |
100 | 128.5±15.7** (31.6±3.5) | 153.4±15.9** (30.4±3.3) | 71.8±7.8** (28.6±3.2) |
Testosterone 10−7 M | 110.0±11.6 (13.5±2.3) | 169.8±18.4** (45.1±4.6) | 69.9±7.8** (24.3±2.6) |
**, P<0.01, vs. untreated control cells. PDS-C, panaxadiol saponins component; CFU-GM, colony formation unit granulocyte and macrophage; CFU-E, colony formation unit-erythroid; CFU-MK, colony formation unit megakaryocytic progenitor.