Table 2. PDS-C increased the colony formation of granulocytic, erythroid and megakaryocytic progenitor cells in AA mice (, n=8).
PDS-C (mg/L) | CFU-GM number (increasing %) | CFU-E number (increasing %) | CFU-MK number (increasing %) |
---|---|---|---|
0 | 31.2±3.3 | 39.8±6.5 | 26.3±2.4 |
5 | 35.1±3.6 (13.1±3.4) | 44.7±8.7 (13.0±1.9) | 29.4±4.2 (12.1±2.0) |
10 | 41.1±3.8** (32.5±4.9) | 52.4±5.3** (31.1±4.3) | 34.1±4.3** (29.7±3.7) |
25 | 46.5±4.1** (49.2±6.1) | 60.3±6.1** (51.6±6.7) | 39.6±5.2** (50.4±6.1) |
50 | 47.5±8.4** (52.1±7.3) | 61.0±6.1** (53.1±7.4) | 40.1±4.9** (53.2±7.1) |
100 | 42.3±4.0** (34.9±1.6) | 54.0±6.0** (35.1±5.3) | 35.1±4.9** (34.2±7.1) |
Testosterone 10−7 M | 36.0±3.7 (15.1±3.5) | 63.0±6.1** (58.3±7.7) | 33.7±4.2** (28.1±3.5) |
**, P<0.01, vs. untreated control cells. PDS-C, panaxadiol saponins component; CFU-GM, colony formation unit granulocyte and macrophage; CFU-E, colony formation unit erythroid; CFU-MK, colony formation unit megakaryocytic progenitor.