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. 2022 Jan;10(2):56. doi: 10.21037/atm-21-6405

Figure 4.

Figure 4

Inhibition of REV-ERBα can elevate the expression of NF-κB in lung cancer cells. (A) Western blot analysis showed the expression of REV-ERBα, p53, and NF-κB under different treatments. (B) Statistics of western blot analysis of the expression level of REV-ERBα, p53, and NF-κB (*P<0.05). (C) Representative images of immunostaining analysis on the effects of downregulation of REV-ERBα on NF-κB (scale bar, 25 µm). (D) Statistical results of immunostaining analysis on the effects of downregulation of REV-ERBα on NF-κB (*P<0.05). Cell nuclei were stained with Hoechst 33342 showing a blue fluorescence. NF-κB, nuclear factor-κB.